Dosage and protocol evidence
Each card states what the quantities are based on. A third-party or animal schedule is not a validated human dose.
Finished-formula concentrations of 0.0015%-0.005% correspond to 15-50 ppm; 10 mg supplies 200 g of a 0.005% formula
Manufacturer-oriented testing used topical application twice daily for 28 days. The calculation does not validate injection or establish independent clinical efficacy.
View source10 mg SNAP-8 plus 0.5 g cosmetic GHK-Cu in 30 mL hyaluronic-acid serum, applied in a pea-sized amount twice daily and used within three weeks
This is a community topical formulation, not clinical evidence. The same discussion warns that commercial percentage claims often refer to a pre-diluted ingredient and cannot be compared without actual peptide mass; raw/peptide-education/pe-ghk-cu.md:4784-4799 and raw/discussions/disc-skin-care.md:438-457.
View sourceReconstituted powder is blended into a serum at roughly 5-10% - an expert example uses about 3 g SNAP-8 in 30 mL for a 10% serum, starting near 5% and working up - and applied twice daily to the face
Forum provenance from an authenticated archive with usernames omitted. The archive states plainly that SNAP-8 is topical only and not for injection, and clarifies that commercial premade solutions are about 0.05% actual peptide, so lyophilised-vial percentages are far higher and more expensive. Route is preserved as topical and not interconverted to an injected quantity.
View sourceEvidence summary
A cosmetic signalling peptide developed for topical formulations. Laboratory and skin-product evidence does not support systemic injection.
Protocol basis
The evidence is formulation-specific to topical cosmetic use. No injectable protocol is presented because none is supported by matched human evidence.
Community provenance (Peppys)
An authenticated research-forum archive treats SNAP-8 strictly as a topical anti-wrinkle active: the powder is reconstituted and blended into a serum base, with an expert example of about 3 g in 30 mL for a 10% serum and advice to begin nearer 5%, applied to the face twice daily. The archive states plainly that SNAP-8 is topical only and not for injection, and notes that commercial premade solutions contain only about 0.05% actual peptide. Usernames and post numbers are omitted, and no injectable schedule is derived because the reports describe topical formulation only.
What remains uncertain
Systemic pharmacokinetics, injection safety, target engagement and clinical outcomes are unknown.