SingleInvestigationalPhase 2Moderate confidenceSourced

Eloralintide

A once-weekly selective amylin receptor agonist in phase 3 development, with published phase 2 arms spanning fixed and escalated 1 mg to 9 mg targets.

Evidence context, not a personal protocol

Quantities below reproduce their stated source context—label, human study, laboratory work or educational guide. They do not assess suitability, product equivalence or individual risk.

Published phase 2 design

Weekly research quantities

The simplified line uses one maximum per arm. The 9 mg line reproduces the published 3 mg to 6 mg to 9 mg progression with four weeks at each lower stage.

Evidence source

Maximum study quantityChoose the maximum shown by the evidence line. Any earlier point can be selected below for its arithmetic.

Assigned weekly quantities

Select a point for its calculation examples

Weeks 1 to 4
3 mg
Weeks 5 to 8
6 mg
+3 mg after 4 weeks
Weeks 9 to 48
9 mg
+3 mg after 4 weeks

Vial-aware arithmetic

Reconstitution examples, up to 3 mL

Choose the vial quantity and BAC water first. The diagram and results below update for the selected 3 mg study quantity. Higher-strength vials may naturally land outside the 20-30 unit band.

Vial quantity

Choose the quantity printed on the vial.

BAC water added

Use 1, 2 or 3 mL, or enter a custom volume up to 3 mL.

Open the full reverse calculator

Three millilitre research vial, diluent vial and capped U-100 syringe on an ink-blue surface — One small vial, one measured diluent volume and one U-100 scale. The arithmetic connects all three.

BAC water selected

1 mL

Basic example limit: 3 mL maximum. Check the actual vial and product-specific limits.

U-100 draw30 U

20-30 U reference band

1 mL BAC

30 units

resulting U-100 draw

Concentration: 10 mg/mL
BAC added: 1 mL

Shown in the diagram. Closest of these examples to 25 units.

2 mL BAC

60 units

resulting U-100 draw

Concentration: 5 mg/mL
BAC added: 2 mL

3 mL BAC

90 units

resulting U-100 draw

Concentration: 3.333 mg/mL
BAC added: 3 mL

Formula: draw units = selected mg × BAC mL ÷ vial mg × 100. The 20-30 unit band is a measurement reference, not a recommendation. Results are mathematical examples, not preparation instructions.

Dosage and protocol evidence

Each card states what the quantities are based on. A third-party or animal schedule is not a validated human dose.

Human StudySubcutaneousOnce weekly

Adults with obesity or overweight and at least one related comorbidity

Once-weekly subcutaneous phase 2 arms at 1 mg, 3 mg, 6 mg or 9 mg, plus 6-to-9 mg and 3-to-6-to-9 mg escalation arms

The 48-week randomized study compared fixed and escalated research arms with placebo; it is not prescribing guidance.

View source

Evidence summary

A once-weekly selective amylin receptor agonist in phase 3 development, with published phase 2 arms spanning fixed and escalated 1 mg to 9 mg targets.

Protocol basis

The protocol summary comes from a published 48-week randomized phase 2 trial and is presented as fixed and escalated study arms.

What remains uncertain

Phase 3 outcomes, authorised labelling, long-term benefit-risk and equivalence to unregulated vials remain unresolved.

Warnings and contraindications

Eloralintide is investigational and has no authorised routine-use schedule.

Phase 2 arms were assigned research designs with trial monitoring.

Gastrointestinal tolerability and escalation findings are population- and protocol-specific.

Organised research bench with labelled storage tray, vial rack, notebook and thermometer — A clean workspace supports traceability. It does not establish sterility.

Shared across protocols

Supplies and general handling

Keep the universal checklist short. Product-specific labelling and source documentation always take priority over a general guide.

Research vial

Select the labelled vial quantity used in the calculation.

View Peppys vial

Bacteriostatic water

Use only a diluent appropriate to the research method and formulation.

View Peppys BAC water

U-100 measuring syringe

Use a new sterile device for every entry. Source locally.

Source locally

Wipes and sharps container

Plan clean handling and immediate sharps disposal. Source locally.

Source locally

Storage follows the label

Do not apply a universal refrigerator rule. Follow the product, diluent and study documentation for temperature, light and expiry.

Use sterile equipment once

CDC injection-safety guidance calls for a new sterile needle and syringe for each injection and entry into a medication container.

Stability is formulation-specific

Do not infer a post-mixing lifetime from BAC water alone. Discard material when identity, integrity or sterility is in doubt.

General references: CDC injection safety, NHS medicine storage and DailyMed BAC water labelling.