Protocol library
SingleInvestigationalPhase 2Moderate confidenceSourced

ARA-290 / Cibinetide

An erythropoietin-derived tissue-protective peptide studied in small phase 2 neuropathy trials. Schedules are disease-specific and remain investigational.

Evidence context, not a personal protocol

Quantities below reproduce their stated source context—label, human study, laboratory work or educational guide. They do not assess suitability, product equivalence or individual risk.

Dosage and protocol evidence

Each card states what the quantities are based on. A third-party or animal schedule is not a validated human dose.

Human Study
Adults with type 2 diabetes and painful neuropathy

4 mg subcutaneously once daily for 28 days

This phase 2 schedule was followed by another 28 days of observation and is not a routine-use protocol.

View source

Evidence summary

An erythropoietin-derived tissue-protective peptide studied in small phase 2 neuropathy trials. Schedules are disease-specific and remain investigational.

Protocol basis

The page reports the repeated 28-day subcutaneous research design used in small neuropathy studies, with the population and monitoring context attached.

What remains uncertain

Larger confirmatory trials, long-term safety, approved indications and equivalence to commercial research vials remain unresolved.

Warnings and contraindications

ARA-290 remains investigational and is not a general neuropathy treatment.
The cited daily schedule was tested for 28 days in small monitored studies.
Results from specific neuropathy populations do not establish broader use.